Coma
Il paziente è fortemente incosciente e non è risvegliabile, nemmeno con stimolazione dolorosa; può presentare diversi gradi di profondità (precoma e quattro stadi di coma) che si differenziano in base ai segni neurologici ed elettroencefalografici (scomparsa dei riflessi cutanei, tendinei periferici, poi del riflesso corneale e infine di quello pupillare alla luce).
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